用3d打印机做个DNA模型吧
时间：2012-08-09 18:06 来源：未知 作者：admin 阅读：次
核苷酸的目的是为周长要打印出唯一的，所以关闭填充插件。使用乘一次打印多件：在汤姆，我可以打印一次（ STL中对2×2 ） 8 。我也建议升级到SF44 ，它没有灯丝回缩比默认Skeinforge 35更好。看在线升级的方向，有几个涉及未成年人过关。
件有浮雕外缘的一封信，但我还是喜欢打印他们以不同的颜色，使序列明显。请记住： A的传达到T和G的跨越C的链接的链接。执行此配对的单元形状。您可能还注意到，在链接的是小于GC的连接安全：这是故意的，模拟的事实，气相色谱对三纲的联系，同时对链接只有两个。
参与创建螺旋片，沿耳轮骨干单元链接只是排队沿外缘有一些奇怪的角度。信件是面向这样，如果你读组装的顺序从左至右，你会阅读从5 '端至3'链，这是报告的DNA序列的约定。
包括OpenSCAD文件的情况下，你想看到我如何为蓝本，或更改。它也有一个组装功能，允许你指定一个序列，它会显示相应的单螺旋。你必须做一个互补序列，以及看到完整的双螺旋。
这些作品打印出来，很快，它并不需要很长时间，做一个好股（我可以做在一个半小时，约30个碱基对） 。然而，准备等待一段时间，如果你想打印出所有2.9亿美元的人类基因组碱基对。
【以下是原文】
The nucleotides are intended to be printed out as perimeters only, so turn off the fill plugin. Use Multiply to print more pieces at once: on a TOM I can print eight at a time (2x2 of the STL pair). I also recommend upgrading to SF44, which does filament retraction better than the default Skeinforge 35. Look up directions for upgrading online, as there are a couple of minor tricks involved.
The pieces have their letter embossed on their outer edges, but I still prefer to print them in different colors to make the sequence obvious. Remember: A's link across to T's and G's link across to C's. The snap shapes enforce this pairing. You may also notice that the A-T link is less secure than the G-C link: this is intentional, to model the fact that G-C pairs link by three bonds while A-T pairs link by only two.
There are some odd angles involved in creating a helix out of flat pieces, so the snap links along the helix backbone are only meant to line up along the outer edg
e. The letters are oriented such that if you read an assembled sequence from left to right, you'll be reading from the 5' end to the 3' end of the strand, which is the convention for reporting DNA sequences.
The OpenSCAD file is included in case you want to see how I modeled this or make changes. It also has an assembly function that allows you to specify a sequence and it will display the corresponding single helix. You'll have to make a complementary sequence as well to see the full double-helix.
These pieces print out so quickly that it doesn't take long to make a good strand (I can do about 30 base pairs in an hour and a half). However, be prepared to wait awhile if you want to print out all 2.9 billion base pairs of the human genome.
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